This guide offers an overview of Sapiens Genetics’ oncology panel services, covering a range of hereditary and somatic cancer testing options designed to meet the needs of modern oncology. It provides insights into our specialized panels, highlighting how Sapiens Genetics empowers healthcare providers with precision diagnostics for informed decision-making in cancer care.
Why Choose Sapiens?
Sapiens Genetics leads in precision oncology, offering advanced genetic testing for hereditary and somatic cancers. Our expert team, extensive gene coverage, and fast turnaround times empower healthcare professionals to make data-driven, personalized treatment decisions. With high standards, personalized reporting, and strong collaborations with leading institutions, Sapiens Genetics ensures secure and ethical handling of patient data, making us a trusted partner in oncology diagnostics.
I. Germline Cancer Panels: Hereditary Cancer Risk Assessments
Our germline cancer panels are specifically designed for individuals with a family history of cancer or other genetic predispositions. These tests provide critical insights into inherited cancer risks, allowing patients to take proactive steps toward prevention and early detection.
- Cancer Predict (57 Genes)
This focused panel screens for mutations across 57 genes linked to various hereditary cancers, providing essential information on genetic risks. - Cancer Predict Expanded (148 Genes)
A more extensive panel, analyzing 148 genes to give a comprehensive view of hereditary cancer risk. Ideal for cases requiring an expanded genetic investigation.
II. Somatic Cancer Panels: Actionable Insights for Tumor Profiling
A. Organ-Specific Panels
Our organ-specific somatic panels provide detailed mutation profiles for various cancer types, directly informing precision treatment strategies.
- Sapiens Lung: Lung Cancer Panel
Utilizing a 17-gene RNA sequencing analysis, this panel detects fusion genes and partial sequence variants, providing insights essential for lung cancer therapies. - Sapiens Sarcoma: Sarcoma Panel
This 63-gene RNA sequencing panel, specialized for sarcomas, reveals important fusions and sequence variants, enabling accurate diagnosis and treatment planning. - Sapiens Colon: Colon Cancer Panel
Combining a 67-gene DNA sequencing analysis with MSI (microsatellite instability) testing, this panel provides crucial genetic details for colorectal cancer treatment options.
B. Pan-Cancer Panels
Our pan-cancer panels offer broad-spectrum tumor profiling across multiple cancer types. These comprehensive panels are ideal for cases requiring an extensive overview of tumor mutations, with additional analyses available for deeper insights.
- Sapiens Pan-Cancer Focus Panels
Designed for compact, in-depth somatic analysis, these panels range from 20 to 523 genes, with options for MSI, TMB (tumor mutational burden), and HRR (homologous recombination repair) testing. Key options include:- 20- and 25-gene DNA analysis with MSI testing for foundational genetic profiling.
- 36-gene RNA analysis to detect fusion genes and sequence variations.
- 76-gene panel with BRCA1/2 and HRR genes, ideal for cases requiring homologous recombination repair insights.
- 523-gene panel with MSI, TMB analysis, and optional MYRIAD-HRD scoring for comprehensive tumor profiling.
- Sapiens Liquid Biopsy Panels
For situations where traditional biopsies are not possible, our liquid biopsy panels analyze circulating tumor DNA (ctDNA) from blood samples. Options include:- EGFR ctDNA sequencing for lung cancer.
- 28- and 146-gene ctDNA panels for broader mutation profiles, with fusion analysis in the 146-gene panel.
- 523-gene ctDNA panel offering extensive somatic analysis with MSI, TMB, and a 23-gene fusion capacity, ideal for high-detail tumor profiling.
Patient Journey and Testing Process
From sample collection to reporting, we ensure a seamless experience. The process is structured as follows:
- Sample Collection: Easy sample collection guidelines are provided.
- Genetic Analysis: Using advanced sequencing technology, the genetic analysis is completed.
- Results & Reporting: Comprehensive, clinician-friendly reports are provided with clear summaries and detailed analyses.
- Consultation: Our experts offer personalized consultations based on the test results, helping clinicians make informed decisions.
Guide & Resources
In our Guide & Resources section, healthcare professionals can access our Sample Reports.
Discover the future of precision oncology with Sapiens Genetics—where groundbreaking science meets personalized care.
